{"id":190,"date":"2018-10-15T16:04:52","date_gmt":"2018-10-15T07:04:52","guid":{"rendered":"http:\/\/blog.knee.or.jp\/about-oa\/?p=190"},"modified":"2020-01-15T21:03:00","modified_gmt":"2020-01-15T12:03:00","slug":"safety-regenerative","status":"publish","type":"post","link":"https:\/\/www.knee.or.jp\/about-oa\/safety-regenerative\/","title":{"rendered":"\u3010\u81ea\u5206\u306e\u8102\u80aa\u3068\u8840\u6db2\u3067\u6cbb\u7642\u3011\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u306e\u518d\u751f\u533b\u7642\u306e\u52b9\u679c\u3068\u5b89\u5168\u6027"},"content":{"rendered":"

\u5f93\u6765\u304b\u3089\u306e\u4fdd\u5b58\u7642\u6cd5\u4ee5\u5916\u3067\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7<\/a>\u3092\u6cbb\u7642\u3059\u308b\u65b9\u6cd5\u3068\u3057\u3066\u3001\u518d\u751f\u533b\u7642\u304c\u6ce8\u76ee\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3069\u306e\u3088\u3046\u306a\u3082\u306e\u304c\u3042\u308a\u3001\u3069\u3046\u3044\u3063\u305f\u4f5c\u7528\u3092\u671f\u5f85\u3067\u304d\u308b\u306e\u304b\u3002\u307e\u305f\u3001\u5b89\u5168\u6027\u306f\u78ba\u4fdd\u3055\u308c\u3066\u3044\u308b\u306e\u304b\u3002\u6c17\u306b\u306a\u308b\u518d\u751f\u533b\u7642\u306e\u30dd\u30a4\u30f3\u30c8\u3092\u304a\u8a71\u3057\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u8102\u80aa\u30fb\u8840\u6db2\u7531\u6765\u306e\u518d\u751f\u533b\u7642\u304c\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u306b\u9069\u5fdc<\/h2>\n

\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u306e\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u3001\u69d8\u3005\u306a\u30e1\u30c7\u30a3\u30a2\u3067\u53d6\u308a\u4e0a\u3052\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u305f\u300c\u518d\u751f\u533b\u7642\u300d\u3002\u3053\u308c\u306f\u4eba\u9593\u306e\u6301\u3064\u7d44\u7e54\u306e\u50cd\u304d\u306b\u3088\u3063\u3066\u3001\u640d\u50b7\u3057\u305f\u7d44\u7e54\u306e\u4fee\u5fa9\u3084\u3001\u4f4e\u4e0b\u3057\u305f\u6a5f\u80fd\u306e\u88dc\u5b8c\u3092\u56f3\u308b\u3068\u3044\u3046\u5148\u9032\u7684\u306a\u533b\u7642\u3067\u3059\u3002\u5185\u79d1\u7684\u306a\u75be\u60a3\u3092\u6cbb\u7642\u3059\u308b\u305f\u3081\u7814\u7a76\u30fb\u5fdc\u7528\u3055\u308c\u3066\u3044\u308b\u5370\u8c61\u304c\u5f37\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u73fe\u5728\u3067\u306f\u6574\u5f62\u5916\u79d1\u9818\u57df\u3001\u3064\u307e\u308a\u5916\u79d1\u7684\u306a\u75be\u60a3\u306b\u3082\u4f53\u7d30\u80de\uff08\u7d44\u7e54\u3068\u306a\u3063\u305f\u7d30\u80de\uff09\u3084\u5e79\u7d30\u80de\uff08\u7d44\u7e54\u306b\u306a\u308b\u524d\u306e\u672a\u5206\u5316\u306e\u7d30\u80de\uff09\u3092\u6d3b\u7528\u3057\u305f\u6cbb\u7642\u304c\u7528\u3044\u3089\u308c\u3066\u304a\u308a\u3001\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u306b\u3082\u9069\u5fdc\u53ef\u80fd\u306a\u6cbb\u7642\u304c\u5b58\u5728\u3059\u308b\u306e\u3067\u3059\u3002<\/p>\n

2018\u5e7410\u6708\u73fe\u5728\u3001\u5b9f\u969b\u306b\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u306e\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u63d0\u4f9b\u3055\u308c\u3066\u3044\u308b\u518d\u751f\u533b\u7642\u306f\u3001\u8102\u80aa\u3068\u8840\u6db2\u306b\u7531\u6765\u3059\u308b\u3082\u306e\u304c\u4e3b\u6d41\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u8102\u80aa\u7531\u6765\u306e\u518d\u751f\u533b\u7642<\/h3>\n

\u8102\u80aa\u7d44\u7e54\u3092\u9175\u7d20\u3067\u9664\u5916\u3057\u305f\u9593\u8cea\u8840\u7ba1\u7d30\u80de\u7fa4\uff08SVF\uff1aStromal Vascular Fraction\uff09\u3002\u3053\u306e\u8102\u80aa\u7531\u6765\u306e\u7d30\u80de\u7fa4\u306b\u6570\u30d1\u30fc\u30bb\u30f3\u30c8\u542b\u307e\u308c\u308b\u306e\u304c\u3001\u518d\u751f\u533b\u7642\u306b\u304a\u3044\u3066\u91cd\u8981\u306a\u610f\u5473\u3092\u6301\u3064\u3001\u5e79\u7d30\u80de\u3067\u3059\u3002\u5e79\u7d30\u80de\u306b\u306f\u7279\u5b9a\u306e\u7d30\u80de\u306b\u5206\u5316\u3059\u308b\u80fd\u529b\u304c\u3042\u308a\u3001\u8102\u80aa\u7531\u6765\u5e79\u7d30\u80de\uff08ASC\uff1aAdipose-Derived Stromal Cells\uff09\u3082\u4f8b\u5916\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

\u5177\u4f53\u7684\u306a\u6cbb\u7642\u6cd5\u306f\u3001\u4e0b\u8179\u90e8\u306a\u3069\u304b\u3089\u8102\u80aa\u3092\u63a1\u53d6\u3057\u3001\u305d\u3053\u304b\u3089\u62bd\u51fa\u3057\u305fSVF\u3092\u819d\u95a2\u7bc0\u5185\u306b\u6ce8\u5c04\u3059\u308b\u3068\u3044\u3046\u3082\u306e\u3002\u819d\u95a2\u7bc0\u306e\u708e\u75c7\u3092\u6291\u3048\u3001\u75db\u307f\u3092\u7de9\u548c\u3059\u308b\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u307e\u3059\u3002<\/p>\n

\u8102\u80aa\u7531\u6765\u5e79\u7d30\u80de\u6cbb\u7642\u3067\u306f\u8102\u80aa\u3092\u63a1\u53d6\u3059\u308b\u305f\u3081\u300130\u5206\u7a0b\u5ea6\u306e\u624b\u8853\uff08\u7f8e\u5bb9\u5916\u79d1\u306e\u8102\u80aa\u5438\u5f15\u306e\u8102\u80aa\u5438\u5f15\u91cf\u304c\u5c11\u306a\u3044\u3082\u306e\u3068\u3044\u3046\u30a4\u30e1\u30fc\u30b8\u3002\u63a1\u53d6\u91cf\u306f\u4e21\u819d\u3067200ml\u7a0b\u5ea6\uff09\u3092\u884c\u3044\u307e\u3059\u304c\u3001\u30e1\u30b9\u3067\u819d\u3092\u5207\u958b\u3059\u308b\u5fc5\u8981\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n

 <\/p>\n

\u5f53\u9662\u3067\u306f\u8102\u80aa\u7531\u6765\u5e79\u7d30\u80de\u3092\u5897\u3084\u3059\u300c\u57f9\u990a\u5e79\u7d30\u80de\u6cbb\u7642\u300d\u3092\u63d0\u4f9b<\/h4>\n

\u8102\u80aa\u7531\u6765\u5e79\u7d30\u80de\u3092\u591a\u304f\u62bd\u51fa\u3057\u819d\u95a2\u7bc0\u3078\u6ce8\u5165\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u3042\u308b\u7a0b\u5ea6\u306e\u8102\u80aa\u91cf\u304c\u5fc5\u8981\u3067\u3059\u3002\u3054\u304f\u5c0f\u3055\u306a\u51e6\u7f6e\u3067\u3059\u304c\u3001\u9ad8\u9f62\u8005\u3084\u8102\u80aa\u306e\u5c11\u306a\u3044\u75e9\u305b\u578b\u306e\u4eba\u306b\u306f\u4e0d\u5b89\u8981\u7d20\u3067\u3082\u3042\u308b\u3067\u3057\u3087\u3046\u3002\u305d\u3053\u3067\u9078\u629e\u3055\u308c\u305f\u306e\u304c\u3001\u5c11\u3057\u306e\u63a1\u53d6\u91cf(\u5438\u5f15\u8102\u80aa\u91cf\u306f\u3055\u3089\u306b\u5c11\u306a\u304420ml\u7a0b\u5ea6\u300110\u5206\u7a0b\u5ea6\u3067\u7d42\u4e86)\u304b\u3089\u7d30\u80de\u6570\u3092\u5897\u3084\u3059\u3001\u57f9\u990a\u3068\u3044\u3046\u65b9\u6cd5\u3067\u3059\u3002<\/p>\n

\u5f53\u9662\u3067\u306f\u3001\u5e79\u7d30\u80de\u306e\u62bd\u51fa\u3068\u57f9\u990a\u3092\u5c02\u9580\u306e\u7d30\u80de\u52a0\u5de5\u65bd\u8a2d\u3078\u59d4\u8a17\u3002\uff16\u9031\u9593(\u6cd5\u5f8b\u3067\u6c7a\u3081\u3089\u308c\u305f\u611f\u67d3\u75c7\u304c\u7121\u3044\u304b\u3069\u3046\u304b\u306e\u691c\u67fb2\u9031\u9593\u3092\u542b\u3080)\u307b\u3069\u304b\u3051\u3066\u57f9\u990a\u3057\u305f\u3082\u306e\u3092\u819d\u95a2\u7bc0\u306b\u6ce8\u5c04\u3059\u308b\u3001\u57f9\u990a\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u5e79\u7d30\u80de\u3092\u57f9\u990a\u3057\u305f\u5834\u5408\u3068\u57f9\u990a\u3057\u306a\u3044\u5834\u5408\u3067\u52b9\u679c\u306e\u9055\u3044\u304c\u3042\u308b\u306e\u304b\u3001\u5f53\u30af\u30ea\u30cb\u30c3\u30af\u3067\u884c\u3063\u305f\u5b9f\u969b\u306e\u6cbb\u7642\u30c7\u30fc\u30bf\u3092\u96c6\u3081\u30012019\u5e74\u306e\u518d\u751f\u533b\u7642\u5b66\u4f1a\u306b\u3066\u767a\u8868\u3057\u307e\u3057\u305f\u3002\u8a73\u3057\u304f\u306f\u4e0b\u8a18\u8a18\u4e8b\u3092\u3054\u53c2\u7167\u304f\u3060\u3055\u3044\u3002
\n[\u8a73\u7d30]\u819d\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u3064\u3044\u3066\u3001\u57f9\u990a\u3057\u305f\u5834\u5408\u306e\u52b9\u679c\u3092\u691c\u8a3c<\/a><\/p>\n

\"\u57f9\u990a\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u6d41\u308c\"<\/p>\n

 <\/p>\n

\u8840\u6db2\u7531\u6765\u306e\u518d\u751f\u533b\u7642<\/h3>\n

\u8840\u6db2\u3092\u5229\u7528\u3057\u305f\u518d\u751f\u533b\u7642\u306e\u4ee3\u8868\u7684\u306a\u3082\u306e\u304c\u3001PRP\u7642\u6cd5\u3067\u3059\u3002PRP\uff08Platelet Rich Plasma\uff09\u3068\u306f\u3001\u591a\u8840\u5c0f\u677f\u8840\u6f3f\u306e\u3053\u3068\u3002\u8840\u5c0f\u677f\u306f\u3001\u76ae\u819a\u306b\u50b7\u304c\u3067\u304d\u305f\u3068\u304d\u306a\u3069\u306b\u8840\u6db2\u3092\u51dd\u56fa\u3055\u305b\u308b\u5f79\u5272\u3092\u679c\u305f\u3059\u7d44\u7e54\u3067\u3001\u3053\u306e\u8840\u5c0f\u677f\u304c\u56fa\u307e\u308b\u969b\u306b\u306f\u69d8\u3005\u306a\u6210\u9577\u56e0\u5b50\u304c\u653e\u51fa\u3055\u308c\u307e\u3059\u3002\u305d\u3046\u3057\u305f\u6210\u9577\u56e0\u5b50\u304c\u3001\u640d\u50b7\u3057\u305f\u7d44\u7e54\u306e\u4fee\u5fa9\u306b\u5927\u304d\u304f\u5bc4\u4e0e\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/p>\n

PRP\u7642\u6cd5\u3067\u306f\u3001\u63a1\u53d6\u3057\u305f\u8840\u6db2\u3092\u9060\u5fc3\u5206\u96e2\u306b\u304b\u3051PRP\u3092\u751f\u6210\u3057\u3001\u819d\u95a2\u7bc0\u306b\u6ce8\u5165\u3057\u307e\u3059\u3002\u640d\u50b7\u3057\u305f\u7d44\u7e54\u306e\u4fee\u5fa9\u3092\u4fc3\u3059\u4f5c\u7528\u3092\u6301\u3064TGF-\u03b2\u3084CTGF\u3068\u3044\u3063\u305f\u6210\u9577\u56e0\u5b50\u306e\u50cd\u304d\u306b\u3088\u3063\u3066\u3001\u708e\u75c7\u3084\u75db\u307f\u306a\u3069\u95a2\u7bc0\u5185\u306e\u30c8\u30e9\u30d6\u30eb\u3092\u6539\u5584\u3059\u308b\u306e\u304c\u72d9\u3044\u3067\u3059\u3002<\/p>\n

\u6700\u8fd1\u3067\u306fPRP\u3092\u3055\u3089\u306b\u7cbe\u88fd\u3057\u3066\u6fc3\u5ea6\u3092\u9ad8\u3081\u3001\u52b9\u679c\u3092\u5897\u5927\u3055\u305b\u305fAPS\uff08Autologous Protein Solution\uff09\u6cbb\u7642\u3082\u81e8\u5e8a\u306b\u7528\u3044\u3089\u308c\u59cb\u3081\u3066\u3044\u307e\u3059\u3002<\/p>\n

\"PRP\u306b\u542b\u307e\u308c\u308b\u6210\u9577\u56e0\u5b50\"<\/p>\n

 <\/p>\n

\u5f53\u9662\u3067\u306fPRP\u3092\u6fc3\u7e2e\u3057\u305f\u300cPRP-FD\u300d\u3092\u63d0\u4f9b<\/h4>\n

\"PRP-FD\u6ce8\u5c04\"\u5f53\u9662\u3067\u63d0\u4f9b\u3057\u3066\u3044\u308b\u306e\u306f\u3001PRP-FD\u6ce8\u5c04\u3002PRP\u7642\u6cd5\u3068\u540d\u524d\u306f\u4f3c\u3066\u3044\u307e\u3059\u304c\u3001\u624b\u6cd5\u304c\u5c11\u3057\u7570\u306a\u308a\u307e\u3059\u3002PRP\u7642\u6cd5\u306f\u6210\u9577\u56e0\u5b50\u3092\u542b\u3080\u591a\u8840\u5c0f\u677f\u8840\u6f3f\uff08\u8840\u5c0f\u677f\u3092\u8c4a\u5bcc\u306b\u542b\u3080\u6db2\u4f53\u6210\u5206\uff09\u3092\u819d\u95a2\u7bc0\u306b\u6ce8\u5c04\u3057\u307e\u3059\u304c\u3001PRP-FD\u6ce8\u5c04\u3067\u306f\u3001\u591a\u8840\u5c0f\u677f\u8840\u6f3f\u304b\u3089\u53d6\u308a\u51fa\u3057\u305f\u6210\u9577\u56e0\u5b50\u3092\u6fc3\u7e2e\u3057\u3066\u6ce8\u5165\u3057\u307e\u3059\u3002
\n\u6cd5\u5f8b\u4e0a\u3067\u306e\u518d\u751f\u533b\u7642\u306f\u7d30\u80de\u6cbb\u7642\u3092\u60f3\u5b9a\u3057\u3066\u3044\u307e\u3059\u304c\u3001PRP-FD\u306f\u88fd\u9020\u5de5\u7a0b\u3067\u7121\u7d30\u80de\u306b\u306a\u308b\u305f\u3081\u3001\u53b3\u5bc6\u306b\u306f\u518d\u751f\u533b\u7642\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u5f53\u9662\u306e\u75c7\u4f8b\u306b\u304a\u3044\u3066\u305d\u306e\u4f5c\u7528\u306fPRP\u306b\u905c\u8272\u306a\u304f\u3001\u307e\u305f\u7121\u7d30\u80de\u5316\u3057\u3066\u3044\u308b\u305f\u3081\u304b\u3001\u6cbb\u7642\u5f8c\u306e\u75db\u307f\u304c\u5c11\u306a\u3044\u3068\u3044\u3046\u808c\u611f\u304c\u3042\u308a\u307e\u3059\u3002
\n\u307e\u305f\u3001PRP-FD\u306f\u7121\u7d30\u80de\u5316\u3057\u3066\u3044\u308b\u305f\u3081\u304b\u3001\u6cbb\u7642\u5f8c\u306b\u7d30\u80de\u304c\u4f5c\u7528\u3059\u308b\u969b\u306b\u8d77\u3053\u308b\u53cd\u5fdc\u75db\u304c\u5c11\u306a\u3044\u3068\u3044\u3046\u808c\u611f\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n

\uff082019\u5e744\u670825\u65e5\u8ffd\u8a18\uff09
\n\u5f53\u9662\u306e\u75c7\u4f8b\u6bd4\u8f03\uff08PRP<\/span>\uff1a14<\/span>\u4f8b15<\/span>\u819d\uff0fPRP-FD<\/span>\uff1a37<\/span>\u4f8b52<\/span>\u819d\uff09\u306b\u304a\u3044\u3066\u306f\u3001\u75db\u307f\u3092\u6570\u5024\u5316\u3057\u305fVAS<\/span>\u30b9\u30b3\u30a2\u306e\u5e73\u5747\u5024\u304cPRP-FD<\/span>\u306e\u65b9\u304c\u6709\u610f\u306b\u6539\u5584\u3055\u308c\u3066\u3044\u305f\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304a\u308a\u3001\u7b2c18<\/span>\u56de\u65e5\u672c\u518d\u751f\u533b\u7642\u5b66\u4f1a\u7dcf\u4f1a\u3067\u3082\u767a\u8868\u3057\u307e\u3057\u305f\u3002<\/p>\n

 <\/p>\n

\u518d\u751f\u533b\u7642\u306e\u5b89\u5168\u6027\u306b\u554f\u984c\u306f\u3042\u308b\u306e\u304b\uff1f<\/h2>\n

\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u306e\u6cbb\u7642\u306b\u518d\u751f\u533b\u7642\u3068\u3044\u3046\u9078\u629e\u80a2\u304c\u52a0\u308f\u308a\u307e\u3057\u305f\u3002\u6cbb\u7642\u5185\u5bb9\u3084\u671f\u5f85\u3067\u304d\u308b\u52b9\u679c\u306f\u7406\u89e3\u3067\u304d\u3066\u3082\u3001\u6700\u5f8c\u306b\u4e0d\u5b89\u8981\u7d20\u3068\u3057\u3066\u6b8b\u308b\u306e\u306f\u3001\u65b0\u3057\u3044\u6cbb\u7642\u3060\u3051\u306b\u5b89\u5168\u6027\u306f\u78ba\u4fdd\u3055\u308c\u3066\u3044\u308b\u306e\u304b\u3068\u3044\u3046\u70b9\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\u3002<\/p>\n

\u300c\u81ea\u8eab\u306e\u8102\u80aa\u3084\u8840\u6db2\u306b\u7531\u6765\u3059\u308b\u6cbb\u7642\u306e\u305f\u3081\u62d2\u7d76\u53cd\u5fdc\u304c\u8d77\u3053\u308a\u306b\u304f\u304f\u3001\u526f\u4f5c\u7528\u306e\u53ef\u80fd\u6027\u3082\u4f4e\u3044\u300d\u3053\u308c\u306f\u518d\u751f\u533b\u7642\u3068\u3044\u3046\u30ef\u30fc\u30c9\u306b\u4ed8\u968f\u3059\u308b\u6587\u8a00\u3067\u3059\u3002\u7d0d\u5f97\u306f\u3044\u304d\u307e\u3059\u304c\u3001\u8102\u80aa\u7531\u6765\u5e79\u7d30\u80de\u6cbb\u7642\u3084PRP\u6cbb\u7642\u3068\u3044\u3063\u305f\u3001\u81ea\u7531\u8a3a\u7642\u3067\u63d0\u4f9b\u3055\u308c\u3066\u3044\u308b\u518d\u751f\u533b\u7642\u3068\u3001\u5927\u5b66\u75c5\u9662\u7b49\u3067\u7814\u7a76\u6bb5\u968e\u306e\u518d\u751f\u533b\u7642\u304c\u4f55\u6545\u3042\u308b\u306e\u3067\u3057\u3087\u3046\u3002<\/p>\n

 <\/p>\n

\u7814\u7a76\u6bb5\u968e\u306e\u6cbb\u7642\u306f\u4fdd\u967a\u8a3a\u7642\u3092\u76ee\u6307\u3057\u3066\u3044\u308b\u3082\u306e\u304c\u591a\u3044<\/h3>\n

\u7814\u7a76\u6bb5\u968e\u306e\u518d\u751f\u533b\u7642\u3068\u805e\u3044\u3066\u307e\u305a\u601d\u3044\u6d6e\u304b\u3079\u308b\u306e\u304c\u3001\u4eac\u90fd\u5927\u5b66\u306eiPS\u7d30\u80de\u3092\u6d3b\u7528\u3057\u305f\u3082\u306e\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\u3002iPS\u7d30\u80de\u3067\u30de\u30a6\u30b9\u5b9f\u9a13\u3067\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u306e\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u307e\u3060\u975e\u81e8\u5e8a\u7814\u7a76\u3002\u30ac\u30f3\u5316\u306e\u30ea\u30b9\u30af\u306b\u3064\u3044\u3066\u306a\u3069\u3001\u4e3b\u3068\u3057\u3066\u307e\u305a\u5b89\u5168\u6027\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\u6bb5\u968e\u3068\u8a00\u3048\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n

\u305d\u306e\u4ed6\u306b\u3082\u3001\u69d8\u3005\u306a\u5927\u5b66\u3067\u518d\u751f\u533b\u7642\u5206\u91ce\u306e\u7814\u7a76\u304c\u306a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u306a\u304b\u306b\u306f\u3001\u81e8\u5e8a\u8a66\u9a13\u3084\u6cbb\u9a13\u3092\u5b9f\u65bd\u3057\u3066\u3044\u308b\u3082\u306e\u3082\u3002\u5177\u4f53\u7684\u306b\u306f\u4e0b\u8a18\u306e\u3088\u3046\u306a\u6cbb\u7642\u304c\u3042\u3052\u3089\u308c\u308b\u306e\u3067\u3059\u304c\u3001\u3053\u3061\u3089\u306f\u81ea\u7531\u8a3a\u7642\u3067\u306f\u306a\u304f\u3001\u5c06\u6765\u7684\u306b\u85ac\u6a5f\u6cd5\u306e\u3082\u3068\u4fdd\u967a\u8a3a\u7642\u3067\u306e\u63d0\u4f9b\u3092\u76ee\u6307\u3057\u3066\u3044\u308b\u305f\u3081\u3001\u81e8\u5e8a\u7814\u7a76\u3092\u91cd\u306d\u3001\u3055\u3089\u306a\u308b\u5b89\u5168\u6027\u3068\u6709\u52b9\u6027\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u308b\u306e\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n

\uff082020\u5e741\u670815\u65e5\u8ffd\u8a18\uff09
\n\u6628\u5e7412\u6708\u3001\u4eac\u90fd\u5927\u5b66\u306e\u7814\u7a76\u30c1\u30fc\u30e0\u304c\u3001iPS\u7d30\u80de\u304b\u3089\u3064\u304f\u3063\u305f\u819d\u8edf\u9aa8\u79fb\u690d\u306e\u81e8\u5e8a\u7814\u7a76\u8a08\u753b\u3092\u7533\u8acb\u3057\u307e\u3057\u305f\u3002\u305f\u3060\u3001\u5148\u65e5\u306b\u3082\u5206\u5316\u6642\u306b\u4e00\u90e8\u306e\u907a\u4f1d\u5b50\u306b\u7570\u5e38\u304c\u3042\u3063\u305f\u306a\u3069\u306e\u5831\u9053\u304c\u3042\u308a\u3001\u540c\u6642\u306b\u9032\u3081\u3089\u308c\u3066\u3044\u308b\u304c\u3093\u5316\u306e\u6709\u7121\u3092\u753b\u50cf\u3067\u78ba\u8a8d\u3059\u308b\u4ed5\u7d44\u307f\u3084\u3001\u50b7\u306e\u5c11\u306a\u3044iPS\u7d30\u80de\u306e\u4f5c\u6210\u6280\u8853\u306e\u78ba\u7acb\u306a\u3069\u3001\u30ea\u30b9\u30af\u56de\u907f\u306e\u7814\u7a76\u306e\u52d5\u5411\u306b\u3082\u6ce8\u76ee\u304c\u96c6\u307e\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u6ed1\u819c\u7531\u6765\u306e\u5e79\u7d30\u80de\u3092\u6d3b\u7528\u3057\u305f\u6cbb\u7642<\/h4>\n

\u819d\u95a2\u7bc0\u3092\u8986\u3063\u3066\u3044\u308b\u6ed1\u819c\u3092\u63a1\u53d6\u3057\u3001\u305d\u3053\u304b\u3089\u62bd\u51fa\u3057\u305f\u5e79\u7d30\u80de\u3092\u819d\u95a2\u7bc0\u306b\u6ce8\u5165\u3059\u308b\u6cbb\u7642\u3067\u3059\u3002\u6771\u4eac\u533b\u79d1\u6b6f\u79d1\u5927\u5b66\u306e\u7814\u7a76\u3067\u3001\u6ed1\u819c\u7531\u6765\u5e79\u7d30\u80de\u306b\u3082\u8edf\u9aa8\u4fdd\u8b77\u3084\u708e\u75c7\u6291\u5236\u306e\u52b9\u679c\u304c\u671f\u5f85\u3067\u304d\u308b\u3068\u660e\u3089\u304b\u306b\u306a\u308a\u3001\u5b9f\u7528\u306b\u5411\u3051\u3066\u7814\u7a76\u304c\u306a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u8edf\u9aa8\u7d30\u80de\u3092\u57f9\u990a\u3057\u3066\u79fb\u690d\u3059\u308b\u6cbb\u7642<\/h4>\n

\u81ea\u8eab\u306e\u8edf\u9aa8\u3092\u63a1\u53d6\u3057\u3066\u5897\u3084\u3057\u305f\u3082\u306e\u3092\u640d\u50b7\u3057\u305f\u90e8\u4f4d\u3078\u79fb\u690d\u3059\u308b\u3001\u81ea\u5bb6\u57f9\u990a\u8edf\u9aa8\u79fb\u690d\u8853\u3068\u3044\u3046\u6cbb\u7642\u6cd5\u304c\u3042\u308a\u307e\u3059\u3002\u5bcc\u58eb\u30d5\u30a3\u30eb\u30e0\u304cCM\u3067\u7d39\u4ecb\u3057\u3066\u3044\u305f\u3001\u5e83\u5cf6\u5927\u5b66\u7814\u7a76\u306e\u3042\u306e\u6280\u8853\u3067\u3059\u3002\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u306b\u306f\u672a\u9069\u5fdc\u3067\u3059\u304c\u3001\u73fe\u72b6\u3001\u30b9\u30dd\u30fc\u30c4\u3084\u4e8b\u6545\u306a\u3069\u306b\u3088\u3063\u3066\u8edf\u9aa8\u3092\u640d\u50b7\u3057\u305f\u5916\u50b7\u6027\u8edf\u9aa8\u6b20\u640d\u75c7\u3084\u3001\u96e2\u65ad\u6027\u9aa8\u8edf\u9aa8\u708e\u3068\u3044\u3046\u75be\u60a3\u306b\u306e\u307f\u4fdd\u967a\u8a3a\u7642\u3067\u63d0\u4f9b\u3055\u308c\u3066\u3044\u308b\u6cbb\u7642\u6cd5\u3067\u3059\u3002<\/p>\n

\u307e\u305f\u3001\u6771\u6d77\u5927\u5b66\u3067\u306f\u60a3\u8005\u306e\u8eab\u4f53\u304b\u3089\u63a1\u53d6\u30fb\u57f9\u990a\u3057\u305f\u8edf\u9aa8\u3092\u30b7\u30fc\u30c8\u72b6\u306b\u3057\u3066\u6b20\u640d\u90e8\u306b\u79fb\u690d\u3059\u308b\u8edf\u9aa8\u7d30\u80de\u30b7\u30fc\u30c8\u3068\u3044\u3046\u6cbb\u7642\u3082\u7814\u7a76\u4e2d\u3002\u8edf\u9aa8\u7d44\u7e54\u306e\u518d\u751f\u306b\u5bc4\u4e0e\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3068\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

\uff082019\u5e744\u670825\u65e5\u8ffd\u8a18\uff09
\n\u6771\u6d77\u5927\u5b66\u306e\u300c\u81ea\u5df1\u7d30\u80de\u30b7\u30fc\u30c8\u306b\u3088\u308b\u8edf\u9aa8\u518d\u751f\u6cbb\u7642\u300d\u306f\u30012019\u5e741\u670810\u65e5\u306b\u958b\u50ac\u3055\u308c\u305f\u539a\u751f\u52b4\u50cd\u7701\u300c\u7b2c71\u56de\u5148\u9032\u533b\u7642\u4f1a\u8b70\u300d\u306b\u304a\u3044\u3066\u3001\u5148\u9032\u533b\u7642\u3068\u3059\u308b\u3053\u3068\u3092\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059[1]\u3002<\/p>\n

 <\/p>\n

\u5f53\u9662\u304c\u81ea\u7531\u8a3a\u7642\u3067\u8102\u80aa\u7531\u6765\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u63d0\u4f9b\u3059\u308b\u7406\u7531<\/h3>\n

\u3055\u3089\u306b\u7814\u7a76\u3092\u91cd\u306d\u308c\u3070\u3001\u4e0a\u8a18\u306e\u3088\u3046\u306a\u6cbb\u7642\u304c\u4fdd\u967a\u8a3a\u7642\u3067\u63d0\u4f9b\u3055\u308c\u308b\u4e16\u306e\u4e2d\u3082\u5922\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u305f\u3060\u3001\u4fdd\u967a\u8a3a\u7642\u306e\u9069\u5fdc\u3068\u306a\u308b\u306e\u3092\u9577\u5e74\u5f85\u3063\u3066\u3044\u308b\u9593\u306b\u3082\u3001\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u306e\u75db\u307f\u306b\u82e6\u3057\u3080\u4eba\u306f\u5897\u3048\u7d9a\u3051\u307e\u3059\u3002\u539a\u751f\u52b4\u50cd\u7701\u306e\u767a\u8868\u306b\u3088\u308c\u3070\u3001\u6f5c\u5728\u7684\u306a\u60a3\u8005\u3092\u542b\u3081\u308b\u3068\u56fd\u5185\u3067\u63a8\u5b9a3000\u4e07\u4eba\u304c\u3053\u306e\u75be\u60a3\u3092\u62b1\u3048\u3001\u305d\u306e\u3046\u30611000\u4e07\u4eba\u306b\u75c7\u72b6\u304c\u51fa\u3066\u3044\u308b\u3068\u3044\u3046\u72b6\u6cc1\u3067\u3059[2]\u3002\u4fdd\u967a\u8a3a\u7642\u3067\u624b\u8efd\u306b\u8ab0\u3067\u3082\u53d7\u3051\u3089\u308c\u308b\u6cbb\u7642\u3092\u5e83\u304f\u63d0\u4f9b\u3059\u308b\u306e\u3082\u3001\u3072\u3068\u3064\u306e\u533b\u7642\u6a5f\u95a2\u306e\u59ff\u3067\u3057\u3087\u3046\u3002\u305f\u3060\u540c\u6642\u306b\u3001\u3053\u306e\u72b6\u6cc1\u3092\u653e\u7f6e\u3059\u308b\u3053\u3068\u3082\u3067\u304d\u307e\u305b\u3093\u3002\u4eca\u3053\u306e\u77ac\u9593\u306b\u8db3\u67b7\u3068\u306a\u3063\u3066\u3044\u308b\u819d\u306e\u75db\u307f\u3092\u53d6\u308a\u9664\u304d\u3001\u3088\u308a\u826f\u3044\u751f\u6d3b\u3092\u9577\u304f\u9001\u3063\u3066\u3044\u305f\u3060\u304f\u305f\u3081\u3001\u79c1\u305f\u3061\u3072\u3056\u95a2\u7bc0\u75c7\u30af\u30ea\u30cb\u30c3\u30af\u306f\u81ea\u7531\u8a3a\u7642\u3067\u518d\u751f\u533b\u7642\u3092\u63d0\u4f9b\u3057\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/p>\n

 <\/p>\n

\u81ea\u7531\u8a3a\u7642\u306e\u518d\u751f\u533b\u7642\u3082\u5b89\u5168\u6027\u306f\u78ba\u4fdd\u3055\u308c\u3066\u3044\u308b<\/h3>\n

\u8102\u80aa\u7531\u6765\u5e79\u7d30\u80de\u6cbb\u7642\u3084PRP\u306a\u3069\u306e\u8840\u6db2\u7642\u6cd5\u3082\u3001\u5927\u5b66\u75c5\u9662\u3067\u7814\u7a76\u3055\u308c\u3066\u308b\u6cbb\u7642\u6cd5\u3068\u7570\u306a\u308b\u304b\u3089\u3068\u3044\u3063\u3066\u5b89\u5168\u6027\u306e\u554f\u984c\u304c\u61f8\u5ff5\u3055\u308c\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3068\u8a00\u3046\u306e\u3082\u3001\u3069\u3061\u3089\u306e\u6cbb\u7642\u6cd5\u3082\u56fd\u5185\u5916\u306e\u81e8\u5e8a\u306b\u304a\u3044\u3066\u5b9f\u65bd\u3055\u308c\u3066\u304a\u308a\u3001\u5909\u5f62\u6027\u819d\u95a2\u7bc0\u75c7\u306b\u5bfe\u3057\u3066\u52b9\u679c\u304c\u3042\u3063\u305f\u3068\u3044\u3046\u5831\u544a\u3082\u591a\u6570\u3002\u305d\u308c\u3060\u3051\u3067\u306a\u304f\u3001\u65e5\u672c\u306b\u304a\u3044\u3066\u306f\u6cd5\u5f8b\u3067\u3082\u4e00\u5b9a\u306e\u5b89\u5168\u6027\u304c\u78ba\u4fdd\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u518d\u751f\u533b\u7642\u7b49\u5b89\u5168\u6027\u78ba\u4fdd\u6cd5\u306e\u65bd\u884c<\/h4>\n

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 <\/p>\n

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